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Rosmarinic acid suppressed cisplatin-induced apoptosis by repressing ROS generation, cytochrome C release, caspase activation, AIF translocation, NF-B activation, IL-1 production, Bax upregulation, and Bcl-2 down-regulation, (Jeong et al

Further, oxidative stress has been proven to facilitate the accumulation of strands of amyloid-beta proteins, normally present in the brain, to form amyloid plaques, which have classically been considered to be the cause and thus, the treatment target of Alzheimers disease

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Anaesthesist 45(4):343350 Spies CD, Reinhart K, Witt I, Meier-Hellmann A, Hannemann L, Bredle DL, Schaffartzik W (1994) Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study